1st Journal Club: Shandra

Shandra Bellinger, Lead Editor of the RIPL_Effect research team, was the first student to give a seminar in the Journal Club series sponsored by the RIPL_Effect research team. She presented a very interesting topic: human immune system manipulation to deliver anti-cancer cytotoxicity to colon and prostate cancer cells. This topic was published by Mitchell et al. in 2014 in the Proceedings of the National Academy of Sciences (click here to access the article). In this study, the authors induced the expression of adhesion molecules commonly expressed the surface of cancer cell on blood-circulating leukocytes. The rationale of inducing these protein is that cancer cells circulating in the blood interact with blood vessels in a manner similar to leukocytes.